If you intend to run 32-bit ASP.NET applications on 64-bit Windows, you must configure IIS to create 32-bit worker processes. For more information about running 32-bit applications on 64-bit Windows, see Running 32-bit Applications on 64-bit Windows.
IIS cannot run 32-bit and 64-bit applications concurrently on the same server.
To enable IIS 6.0 to run 32-bit ASP.NET applications on 64-bit Windows
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Open a command prompt and navigate to the %systemdrive%\Inetpub\AdminScripts directory.
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Type the following command:
cscript.exe adsutil.vbs set W3SVC/AppPools/Enable32BitAppOnWin64 true
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Press ENTER.
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Download and install the Microsoft .NET Framework Version 1.1 Redistributable Package.
See Also